Tuesday Apr 21, 2020
The immune system, CAR-T therapy and cancer
The immune system has become a hot topic recently with COVID-19's spread but did you know that scientists can manipulate the immune system to fight cancer? In this episode we go over the basics of the immune system, discuss how cancer can hijack the immune system and introduce you to CAR-T therapy!
// SOURCES
Types of T-cells: https://www.celiackidsconnection.org/2018/05/06/what-are-the-different-types-of-t-cells/
Great summary of the nature article: https://www.sciencealert.com/new-t-cell-therapy-kills-most-human-cancer-types-and-might-work-across-individuals
Hallmarks of cancer: https://blogs.scientificamerican.com/guest-blog/the-hallmarks-of-cancer-9-reprogramming-energy-metabolism/
Journal article on glycolysis and immune system: https://www.cell.com/cell-metabolism/pdf/S1550-4131(18)30178-5.pdf
Personalis article: https://www.personalis.com/understanding-role-human-leukocyte-antigen-cancer-immunotherapy/
What is CAR-T therapy: https://www.cartcellscience.com/car-t-cell-therapy-frequently-asked-questions/
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